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产品推荐-髓过氧化物酶抗体,Anti-MPO抗体

更新时间:2019-12-17      点击次数:1414
英文名字Rabbit MPO Polyclonal Antibody
中文名称髓过氧化物酶抗体,Anti-MPO抗体
产品货号abs120616
产品报价¥950/50ul,¥1450/100ul
产品描述Myeloperoxidase is an important enzyme used by granulocytes during phagocytic lysis of foreign particles engulfed. In normal tissues and in a variety of myeloproliferative disorders myeloid cells of both neutrophilic and eosinophilic types, at all stages of maturation, exhibit strong cytoplasmic reactivity for MPO. Erythroid precursors, megakaryocytes, lymphoid cells, mast cells, and plasma cells are nonreactive. MPO is not observed in the neoplastic cells of a wide variety of epithelial tumors and sarcomas. MPO is useful in differentiating between myeloid and lymphoid leukemias.
背景Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of netrophils.
保存方法Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
产品说明书

 

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